Pathology Associates Of Lexington, P.A.
Pathology Associates Of Lexington, P.A.
Pathology Associates Of Lexington, P.A.
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        Xiao-Meng "Karen" Xu, M.D., Ph.D.
      

Karen Xu

CURRICULUM VITAE

Current Position: [photo and summary

EDUCATION:
1981-87
M. D. Shanghai Medical University, School of Medicine, Shanghai, China

1987-89
Clinical Pharmacology Residency
Institute of Clinical Pharmacology
Shanghai Medical University, Shanghai, China

1990-94
Ph.D.
The Graduate School of Biomedical Sciences
University of Texas Medical Branch at Galveston, Texas

1994
Postdoctoral Fellowship, Sealy Center for Molecular Biology
University of Texas Medical Branch at Galveston, Texas

1/95-12/98
Pathology Residency (combined anatomic and clinical pathology program)
The UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

PROFESSIONAL EXPERIENCES AND CERTIFICATIONS:

3/00-May 2009
Associate pathologist at Lexington Medical Center, West Columbia, SC (with Pathology Associates of Lexington, P.A.) & picked up about 8 years forensic pathology experience.

3/99-2/00.
Pathology Service, Independent Contractor for Pathology Associates of Lexington, P.A., at Lexington Medical Center, West Columbia, SC

1994 Certified by ECFMG (#0-469-802-3)

1998 American Board of Pathology; certified in Anatomic Pathology/Clinical Pathology

1998 Licensed in the state of New Jersey (#MA067287)

1999 Licensed in the state of South Carolina (#20697)

HONORS:

1996 First place, Resident in Service Slides Contest
Awarded by the Joint Pathology Residency Program of the UMDNJ-Robert Wood Johnson Medical School and the St. Peter's Medical Center, New Brunswick, NJ.

1994 Rose and Harry Walker Research Award
Awarded by the Graduate School of the University of Texas Medical Branch at Galveston, Texas

1992 The James E. Beall II Memorial Award for Academic Excellence.
Awarded by the Graduate School of the University of Texas Medical Branch at Galveston, Texas

1987 Cum Laude Graduate, Shanghai Medical University, School of Medicine, Shanghai, China

RESEARCH ACTIVITIES:

1987 Fructose diphosphate on platelet aggregation and calcium regulation

1987-89 Genetic polymorphism of debrisoquine hydroxylation and sulfadimidine acetylation

1990 Smoking related free radical damage in proteins

1991 Bromobenzene toxicity

1991-94 Steroid receptor molecular and cell biology

1994 Regulation of PTH-like peptide gene expression in breast cancer cells

1996 Mannose 6-phosphate in breast cancer and its clinical correlations

1997 Collagen XV and XVIII expression in human tissues

1998 PCR analysis of DNA from paraffin embedded tissues 

TEACHING EXPERIENCE:

1998 Pathology Course for physician assistants at Robert Wood Johnson Medical School, New Brunswick, NJ

1997 Pathology Case Based Study for medical students at Robert Wood Johnson Medical School, New Brunswick, NJ 

1988-89 Pharmacology Laboratory Course and Medical Pharmacology for medical students at Shanghai Medical University 

ACADEMIC & PROFESSIONAL MEMBERSHIPS

Fellow, College of American Pathologists
Fellow, American Society of Clinical Pathologists
Member, South Carolina Society of Pathologists
Member, South Carolina Medical Association
Member, Lexington Medical Association
Member, American Medical Association 

SELECTED PUBLICATIONS: 

X. K. Xu (2004) Right ventricular fatty replacement as the possible missing link between fatty liver and sudden death.  Med Hypothese Res 1: 253-260. 

Amenta, P.S., Briggs, K., Xu, X., Gamboa, E., Jukkola, A.F., Li, D., and Myers, J.C. (2000) Type XV collagen in human colonic adenocarcinomas has a different distribution than other basement membrane zone proteins. Human Pathology 31(3): 359-66 

Xu, X., and Thomas, M.L. (1995) Biphasic actions of estrogen on colon cancer cell growth: Possible mediation by high- and low- affinity estrogen binding sites. Endocrine 3:661-665. 

Zhang, R.W., Supowit, S.C., Xu, X., Li, H., Christensen, M.D., Lozano, R., and Simmons, D.J. (1995) Expression of selected osteogenic markers in the fibroblast-like cells of rat marrow stroma. Calcified Tissue International 56: 283-291. 

Xu, X., and Thomas, M.L. (1994) Estrogen receptor-mediated direct stimulation of colon cancer cell growth in vitro.  Molecular and Cellular Endocrinology 132: 426-430. 

Thomas, M.L., Xu, X., Norfleet, A.M., and Watson, C.S. (1993) The presence of functional estrogen receptors in intestinal epithelial cells. Endocrinology 132: 426-430. 

Wang, H., Xu, X., Jiang, W., Zhu, J., Guo, Y., Chan, K., and Arnold, K., (1990) An HPLC assay of debrisoquine and 4-hydroxydebrisoquine. Acta Acadamiae Medicinae Shanghai 17: 269-274. 

Xu, X., and Jiang, W. (1990) Debrisoquine hydroxylation and sulfamethazine acetylation in a Chinese population. Acta Pharmacologica Sinica [English Edition] 11:385. 

Xu, X., Jiang, W., and Guo, Y. (1990)  High-performance liquid chromatographic determination of sulfadimidine and N-acetylsulfadimidine in blood. Chinese Pharmacological Bulletin 6:190-200. 

Xu, X., and Jiang, W. (1989) Debrisoquine hydroxylation in a Chinese population. Chinese Journal of Physiological Sciences [English Edition] 5:361-366. 

INVITED PRESENTATIONS AT PROFESSIONAL MEETINGS

Jiang, W.D., and Xu, X. Debrisoquine hydroxylation in a Chinese population. IV World Conference on Clinical Pharmacology and Therapeutics. 1989, Mannheim, Heidelberg. 

Xu, X., Norfleet, A.M., Watson, C.S., and Thomas, M.L., Evidence for the presence of estrogen receptors in rat intestinal epithelium. Proceedings of the 74th Annual Meeting of American Endocrine Society. 1992, San Antonio. 

Xu, X., and Thomas, M.L., High- and low-affinity estrogen binding and estrogen effects on the growth of a colon cancer cell line. Proceedings of the IX International Congress of Hormonal Steroids. 1994, Dallas. 

Xu, X., Stewart, L.V., and Thomas, M.L., Estrogen receptor-mediated direct stimulation of colon cancer cell growth in vitro. Proceedings of the IX International Congress of Hormonal Steroids. 1994, Dallas.

June 2009

 
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